Ruin and Corruption
Available at the start of the quest Beneath the Spire (Act IV)
Covetous Shen:
All is falling to ruin and corruption. Nothing in all my days and all my years has ever compared to this.
Player:
Do not lose hope. Terrible things have come and gone before.
Covetous Shen:
But nowhere near as terrible as might happen if you do not defeat Diablo. All the jewels in Heaven or in our world would mean nothing then. Oh, I weep to think of such a day.